Adenoviral infection of most cells is mediated largely by the coxsackievirus-adenovirus receptor (CAR). In many cells, however, this receptor is either absent or present at extremely low levels, reducing the efficiency of adenovirusuptake.
ViraDuctin™ Adenovirus Transduction Reagent is designed specifically to increase the efficiency of adenoviraltransduction without regard to the level of CAR expression on the surface of the target cells.
*Note: The number of transductions per vial is based on the use of 6-well plates or 35 mm culture dishes. However, this product may also be used with 96-well, 24-well or 12-well plates, as well as 60 mm or 100 mm dishes. See product manual for details.
Enhanced Transduction using the ViraDuctin™ Adenovirus Transduction Reagent. Infection of NIH3T3 cells with recombinant ß-gal Recombinant Adenovirus (#ADV-002). X-gal staining under microscope.
Enhanced Transduction using the ViraDuctin™ Adenovirus Transduction Reagent. Infection of NIH3T3 cells with recombinant ß-gal Recombinant Adenovirus (#ADV-002). Scoring of infection with ViraDuctin™ reagent as a percentage of infection compared to control.
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